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The Genus Solanum: An Ethnopharmacological, Phytochemical and Biological Properties Review.

作者 Kaunda, Joseph Sakah; Zhang, Ying-Jun

期刊 Natural products and bioprospecting , 2019-Apr,2:9

DOI 10.1007/s13659-019-0201-6 PubMed 30868423

摘要 Over the past 30years, the genus Solanum has received considerable attention in chemical and biological studies. Solanum is the largest genus in the family Solanaceae, comprising of about 2000 species distributed in the subtropical and tropical regions of Africa, Australia, and parts of Asia, e.g., China, India and Japan. Many of them are economically significant species. Previous phytochemical investigations on Solanum species led to the identification of steroidal saponins, steroidal alkaloids, terpenes, flavonoids, lignans, sterols, phenolic comopunds, coumarins, amongst other compounds. Many species belonging to this genus present huge range of pharmacological activities such as cytotoxicity to different tumors as breast cancer (4T1 and EMT), colorectal cancer (HCT116, HT29, and SW480), and prostate cancer (DU145) cell lines. The biological activities have been attributed to a number of steroidal saponins, steroidal alkaloids and phenols. This review features 65 phytochemically studied species of Solanum between 1990 and 2018, fetched from SciFinder, Pubmed, ScienceDirect, Wikipedia and Baidu, using Solanum and the species'' names as search terms (all fields).

涉及物种 茄属 Solanum