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Bergenia crassifolia (L.) Fritsch - Pharmacology and phytochemistry

Authors Shikov, Alexander N.; Pozharitskaya, Olga N.; Makarova, Marina N.; Makarov, Valery G.; Wagner, Hildebert

Journal PHYTOMEDICINE , OCT 15 2014,12:21

DOI 10.1016/j.phymed.2014.06.009 PubMed 25442262

Abstract Purpose: Bergenia crassifolia (L.) Fritsch, a species in the Bergenia genus belongs to the family Saxifragaceae, is valuated for its medicinal application. The review focuses on the medicinal uses, phytochemistry, and the biological activities of B. crassifolia to explore its benefits and potential uses.Methods: In this review, we summarized data, published in Russia and in other countries related to B. crassifolia.Results: Rhizomes and leaves of this plant are in use as traditional remedies for the treatment of different disorders in the folk medicine systems of Russia and Asia. The plant is a potential source of tannins, benzanoids, flavonoids, polysaccharides and other active compounds. Due to the presence of a multitude of bioactives, a wide array of pharmacological activities have been ascribed to different parts of this herb and individual compounds, which include adaptogenic, antiinflammatory, antihypertensive, antimicrobial, antioxidant, antiobesity, antitus sive, cerebro-protective, hepatoprotective, immunomodulating, and diuretic.Conclusion: The review highlights the potential of B. crassifolia for further development of herbal medicines on its base. (C) 2014 Elsevier GmbH. All rights reserved.

Species covered 厚叶岩白菜 Bergenia crassifolia