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Two new tirucallane triterpenoids from the leaves of Aquilaria sinensis

作者 Cheng, Jin Tang; Han, Ya Qiong; He, Juan; Wu, Xing De; Dong, Liao Bin; Peng, Li Yan; Li, Yan; Zhao, Qin Shi

期刊 ARCHIVES OF PHARMACAL RESEARCH , SEP 2013,9:36

DOI 10.1007/s12272-013-0088-4 PubMed 23508744

摘要 Two new tirucallane triterpenoids, aquilacallanes A-B (1-2), together with 15 known compounds (3-17) were isolated from the leaves of Aquilaria sinensis. The structures of these new compounds were elucidated on the basis of extensive spectroscopic analyses. All compounds were evaluated for their cytotoxic activity against five human cancer cell lines. The known compounds, ursolic acid (7) and 5,7,4''-trimethoxyflavone (14), exhibited weak cytotoxic activity against some cells.

涉及物种 土沉香 Aquilaria sinensis